Reactivation of Mutant-EGFR Degradation through Clathrin Inhibition Overcomes Resistance to EGFR Tyrosine Kinase Inhibitors.

Ménard, Ludovic

Reactivation of Mutant-EGFR Degradation through Clathrin Inhibition Overcomes Resistance to EGFR Tyrosine Kinase Inhibitors. [electronic resource] - Cancer research 06 2018 - 3267-3279 p. digital

Publication Type: Journal Article

1538-7445

10.1158/0008-5472.CAN-17-2195 doi


Antineoplastic Combined Chemotherapy Protocols--pharmacology
Apoptosis--drug effects
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Line, Tumor
Clathrin--antagonists & inhibitors
Drug Resistance, Neoplasm--drug effects
Endocytosis--drug effects
ErbB Receptors--genetics
Humans
Lung Neoplasms--drug therapy
Lysosomes--metabolism
Mutation
Protein Kinase Inhibitors--pharmacology
Proteolysis--drug effects
Signal Transduction--genetics
Sulfonamides--pharmacology
Thiazolidines--pharmacology