Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic Neurons. [electronic resource]
Producer: 20190423Description: 1251-1266 p. digitalISSN:- 2213-6711
- Actin Depolymerizing Factors -- metabolism
- Animals
- Brain -- pathology
- Calbindin 2 -- metabolism
- Cell Differentiation -- drug effects
- Cell Movement -- drug effects
- Cell Shape -- drug effects
- Cell Survival -- drug effects
- Down Syndrome -- genetics
- GABAergic Neurons -- drug effects
- Gene Expression Profiling
- Gene Expression Regulation -- drug effects
- Humans
- Induced Pluripotent Stem Cells -- drug effects
- Interneurons -- drug effects
- Mice
- Models, Biological
- Neural Stem Cells -- drug effects
- Neurites -- drug effects
- Somatostatin -- pharmacology
- p21-Activated Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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