Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic Neurons.

Huo, Hai-Qin

Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic Neurons. [electronic resource] - Stem cell reports 04 2018 - 1251-1266 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2213-6711

10.1016/j.stemcr.2018.02.001 doi


Actin Depolymerizing Factors--metabolism
Animals
Brain--pathology
Calbindin 2--metabolism
Cell Differentiation--drug effects
Cell Movement--drug effects
Cell Shape--drug effects
Cell Survival--drug effects
Down Syndrome--genetics
GABAergic Neurons--drug effects
Gene Expression Profiling
Gene Expression Regulation--drug effects
Humans
Induced Pluripotent Stem Cells--drug effects
Interneurons--drug effects
Mice
Models, Biological
Neural Stem Cells--drug effects
Neurites--drug effects
Somatostatin--pharmacology
p21-Activated Kinases--metabolism