Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions. [electronic resource]
Producer: 20190708Description: 885-896 p. digitalISSN:- 1538-8514
- Acrylamides
- Aniline Compounds
- Animals
- COS Cells
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor
- Chlorocebus aethiops
- ErbB Receptors -- antagonists & inhibitors
- Exons -- genetics
- Female
- Humans
- Lung Neoplasms -- drug therapy
- Mice, SCID
- Mutation
- Piperazines -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Xenograft Model Antitumor Assays -- methods
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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