Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions.
Floc'h, Nicolas
Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions. [electronic resource] - Molecular cancer therapeutics 05 2018 - 885-896 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1538-8514
10.1158/1535-7163.MCT-17-0758 doi
Acrylamides
Aniline Compounds
Animals
COS Cells
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Line, Tumor
Chlorocebus aethiops
ErbB Receptors--antagonists & inhibitors
Exons--genetics
Female
Humans
Lung Neoplasms--drug therapy
Mice, SCID
Mutation
Piperazines--pharmacology
Protein Kinase Inhibitors--pharmacology
Xenograft Model Antitumor Assays--methods
Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions. [electronic resource] - Molecular cancer therapeutics 05 2018 - 885-896 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1538-8514
10.1158/1535-7163.MCT-17-0758 doi
Acrylamides
Aniline Compounds
Animals
COS Cells
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Line, Tumor
Chlorocebus aethiops
ErbB Receptors--antagonists & inhibitors
Exons--genetics
Female
Humans
Lung Neoplasms--drug therapy
Mice, SCID
Mutation
Piperazines--pharmacology
Protein Kinase Inhibitors--pharmacology
Xenograft Model Antitumor Assays--methods