Regulation of bioenergetics through dual inhibition of aldehyde dehydrogenase and mitochondrial complex I suppresses glioblastoma tumorspheres. [electronic resource]
Producer: 20191008Description: 954-965 p. digitalISSN:- 1523-5866
- Adenosine Triphosphate -- metabolism
- Aldehyde Dehydrogenase -- antagonists & inhibitors
- Animals
- Biomarkers, Tumor -- genetics
- Brain Neoplasms -- metabolism
- Cell Proliferation
- Contraceptive Agents, Male -- pharmacology
- Electron Transport Complex I -- antagonists & inhibitors
- Energy Metabolism -- drug effects
- Gene Expression Profiling
- Gene Expression Regulation, Neoplastic
- Glioblastoma -- metabolism
- Gossypol -- pharmacology
- Humans
- Hypoglycemic Agents -- pharmacology
- Male
- Mice
- Mice, Nude
- Mitochondria -- drug effects
- Neoplasm Invasiveness
- Neoplastic Stem Cells -- drug effects
- Oxidative Phosphorylation -- drug effects
- Phenformin -- pharmacology
- Prognosis
- Survival Rate
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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