Regulation of bioenergetics through dual inhibition of aldehyde dehydrogenase and mitochondrial complex I suppresses glioblastoma tumorspheres.

Park, Junseong

Regulation of bioenergetics through dual inhibition of aldehyde dehydrogenase and mitochondrial complex I suppresses glioblastoma tumorspheres. [electronic resource] - Neuro-oncology 06 2018 - 954-965 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1523-5866

10.1093/neuonc/nox243 doi


Adenosine Triphosphate--metabolism
Aldehyde Dehydrogenase--antagonists & inhibitors
Animals
Biomarkers, Tumor--genetics
Brain Neoplasms--metabolism
Cell Proliferation
Contraceptive Agents, Male--pharmacology
Electron Transport Complex I--antagonists & inhibitors
Energy Metabolism--drug effects
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Glioblastoma--metabolism
Gossypol--pharmacology
Humans
Hypoglycemic Agents--pharmacology
Male
Mice
Mice, Nude
Mitochondria--drug effects
Neoplasm Invasiveness
Neoplastic Stem Cells--drug effects
Oxidative Phosphorylation--drug effects
Phenformin--pharmacology
Prognosis
Survival Rate
Xenograft Model Antitumor Assays