Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy. [electronic resource]
Producer: 20190325Description: 99-116 p. digitalISSN:- 1460-2156
- Animals
- Brain -- enzymology
- Cytokines -- metabolism
- Disease Models, Animal
- Encephalitis -- etiology
- Female
- Genetic Therapy -- methods
- Gliosis -- therapy
- Glycosaminoglycans -- genetics
- Humans
- Liver -- enzymology
- Macrophages -- enzymology
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mucopolysaccharidosis III -- complications
- Prednisolone -- therapeutic use
- Spleen -- enzymology
- Stem Cells -- physiology
- Sulfatases -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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