Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy.
Holley, Rebecca J
Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy. [electronic resource] - Brain : a journal of neurology 01 2018 - 99-116 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1460-2156
10.1093/brain/awx311 doi
Animals
Brain--enzymology
Cytokines--metabolism
Disease Models, Animal
Encephalitis--etiology
Female
Genetic Therapy--methods
Gliosis--therapy
Glycosaminoglycans--genetics
Humans
Liver--enzymology
Macrophages--enzymology
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Mucopolysaccharidosis III--complications
Prednisolone--therapeutic use
Spleen--enzymology
Stem Cells--physiology
Sulfatases--genetics
Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy. [electronic resource] - Brain : a journal of neurology 01 2018 - 99-116 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1460-2156
10.1093/brain/awx311 doi
Animals
Brain--enzymology
Cytokines--metabolism
Disease Models, Animal
Encephalitis--etiology
Female
Genetic Therapy--methods
Gliosis--therapy
Glycosaminoglycans--genetics
Humans
Liver--enzymology
Macrophages--enzymology
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Mucopolysaccharidosis III--complications
Prednisolone--therapeutic use
Spleen--enzymology
Stem Cells--physiology
Sulfatases--genetics