SPARCL1 suppresses osteosarcoma metastasis and recruits macrophages by activation of canonical WNT/β-catenin signaling through stabilization of the WNT-receptor complex. [electronic resource]
Producer: 20190306Description: 1049-1061 p. digitalISSN:- 1476-5594
- Animals
- Apoptosis
- Biomarkers, Tumor -- genetics
- Bone Neoplasms -- genetics
- Calcium-Binding Proteins -- genetics
- Cell Movement
- Cell Proliferation
- Chemokine CCL5 -- genetics
- Extracellular Matrix Proteins -- genetics
- Frizzled Receptors -- genetics
- Gene Expression Regulation, Neoplastic
- Humans
- Low Density Lipoprotein Receptor-Related Protein-5 -- genetics
- Low Density Lipoprotein Receptor-Related Protein-6 -- genetics
- Lung Neoplasms -- genetics
- Macrophages -- metabolism
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Neoplasm Invasiveness
- Osteosarcoma -- genetics
- Tumor Cells, Cultured
- Wnt Proteins -- genetics
- Xenograft Model Antitumor Assays
- beta Catenin -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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