Low copy numbers of complement C4 and homozygous deficiency of C4A may predispose to severe disease and earlier disease onset in patients with systemic lupus erythematosus. [electronic resource]
Producer: 20180917Description: 600-609 p. digitalISSN:- 1477-0962
- Adult
- Aged
- Case-Control Studies
- Chi-Square Distribution
- Complement C4a -- deficiency
- DNA Copy Number Variations
- Drug Therapy, Combination
- Female
- Gene Deletion
- Gene Dosage
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Germany
- HLA-DRB1 Chains -- genetics
- Homozygote
- Humans
- Immunosuppressive Agents -- therapeutic use
- Logistic Models
- Lupus Erythematosus, Systemic -- diagnosis
- Male
- Middle Aged
- Odds Ratio
- Phenotype
- Polymorphism, Single Nucleotide
- Prognosis
- Risk Factors
- Severity of Illness Index
- Time Factors
- Young Adult
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Publication Type: Journal Article
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