Trehalose ameliorates oxidative stress-mediated mitochondrial dysfunction and ER stress via selective autophagy stimulation and autophagic flux restoration in osteoarthritis development. [electronic resource]
Producer: 20180608Description: e3081 p. digitalISSN:- 2041-4889
- Animals
- Apoptosis -- drug effects
- Autophagy -- drug effects
- Chondrocytes -- drug effects
- DNA Damage -- drug effects
- Endoplasmic Reticulum Stress -- drug effects
- Humans
- Membrane Proteins -- genetics
- Mice
- Mitochondrial Proteins -- genetics
- Osteoarthritis -- drug therapy
- Oxidative Stress -- drug effects
- Phosphoprotein Phosphatases -- genetics
- RNA, Small Interfering -- administration & dosage
- RNA-Binding Proteins -- genetics
- Trehalose -- administration & dosage
- tert-Butylhydroperoxide -- toxicity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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