Trimethylamine-N-Oxide Induces Vascular Inflammation by Activating the NLRP3 Inflammasome Through the SIRT3-SOD2-mtROS Signaling Pathway. [electronic resource]
Producer: 20180521ISSN:- 2047-9980
- Animals
- Antioxidants -- pharmacology
- Apoptosis Regulatory Proteins -- metabolism
- Atherosclerosis -- chemically induced
- Cells, Cultured
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Female
- Genetic Predisposition to Disease
- Human Umbilical Vein Endothelial Cells -- drug effects
- Humans
- Inflammasomes -- agonists
- Inflammation Mediators -- metabolism
- Methylamines -- toxicity
- Mice, 129 Strain
- Mice, Knockout, ApoE
- Mitochondria -- drug effects
- NLR Family, Pyrin Domain-Containing 3 Protein -- agonists
- Phenotype
- RNA Interference
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Sirtuin 3 -- deficiency
- Superoxide Dismutase -- metabolism
- Time Factors
- Transfection
- Vasculitis -- chemically induced
No physical items for this record
Publication Type: Journal Article
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