Novel pan PI3K inhibitor-induced apoptosis in APL cells correlates with suppression of telomerase: An emerging mechanism of action of BKM120. [electronic resource]
Producer: 20171113Description: 1-8 p. digitalISSN:- 1878-5875
- Aminopyridines -- pharmacology
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- DNA -- biosynthesis
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Humans
- Leukemia, Promyelocytic, Acute -- pathology
- Morpholines -- pharmacology
- NF-kappa B -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- S Phase -- drug effects
- Signal Transduction -- drug effects
- Telomerase -- antagonists & inhibitors
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Publication Type: Journal Article
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