Novel pan PI3K inhibitor-induced apoptosis in APL cells correlates with suppression of telomerase: An emerging mechanism of action of BKM120.
Bashash, Davood
Novel pan PI3K inhibitor-induced apoptosis in APL cells correlates with suppression of telomerase: An emerging mechanism of action of BKM120. [electronic resource] - The international journal of biochemistry & cell biology 10 2017 - 1-8 p. digital
Publication Type: Journal Article
1878-5875
10.1016/j.biocel.2017.08.009 doi
Aminopyridines--pharmacology
Apoptosis--drug effects
Caspase 3--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
DNA--biosynthesis
Enzyme Activation--drug effects
Enzyme Inhibitors--pharmacology
Humans
Leukemia, Promyelocytic, Acute--pathology
Morpholines--pharmacology
NF-kappa B--metabolism
Phosphoinositide-3 Kinase Inhibitors
S Phase--drug effects
Signal Transduction--drug effects
Telomerase--antagonists & inhibitors
Novel pan PI3K inhibitor-induced apoptosis in APL cells correlates with suppression of telomerase: An emerging mechanism of action of BKM120. [electronic resource] - The international journal of biochemistry & cell biology 10 2017 - 1-8 p. digital
Publication Type: Journal Article
1878-5875
10.1016/j.biocel.2017.08.009 doi
Aminopyridines--pharmacology
Apoptosis--drug effects
Caspase 3--metabolism
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
DNA--biosynthesis
Enzyme Activation--drug effects
Enzyme Inhibitors--pharmacology
Humans
Leukemia, Promyelocytic, Acute--pathology
Morpholines--pharmacology
NF-kappa B--metabolism
Phosphoinositide-3 Kinase Inhibitors
S Phase--drug effects
Signal Transduction--drug effects
Telomerase--antagonists & inhibitors