Mast cells decrease efficacy of anti-angiogenic therapy by secreting matrix-degrading granzyme B. [electronic resource]
Producer: 20171120Description: 269 p. digitalISSN:- 2041-1723
- Angiogenesis Inhibitors -- pharmacology
- Animals
- Anti-Asthmatic Agents -- pharmacology
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cromolyn Sodium -- pharmacology
- Endothelial Cells -- drug effects
- Extracellular Matrix -- drug effects
- Fibroblast Growth Factor 1 -- drug effects
- Fibroblast Growth Factor 2 -- drug effects
- Granulocyte-Macrophage Colony-Stimulating Factor -- drug effects
- Granzymes -- metabolism
- Human Umbilical Vein Endothelial Cells
- Laminin -- metabolism
- Mast Cells -- drug effects
- Mice
- Neoplasms -- blood supply
- Neovascularization, Pathologic -- metabolism
- Vascular Endothelial Growth Factor A -- drug effects
- Vascular Endothelial Growth Factor Receptor-2 -- drug effects
- Vitronectin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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