Cisplatin resistance in non-small cell lung cancer cells is associated with an abrogation of cisplatin-induced G2/M cell cycle arrest. [electronic resource]
Producer: 20171013Description: e0181081 p. digitalISSN:- 1932-6203
- A549 Cells
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Ataxia Telangiectasia Mutated Proteins -- genetics
- Blotting, Western
- Carcinoma, Non-Small-Cell Lung -- genetics
- Carrier Proteins -- genetics
- Cisplatin -- pharmacology
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- DNA-Binding Proteins -- genetics
- Drug Resistance, Neoplasm -- drug effects
- G2 Phase Cell Cycle Checkpoints -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Heat-Shock Proteins -- genetics
- Humans
- Lung Neoplasms -- genetics
- Proto-Oncogene Proteins c-mdm2 -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article
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