KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library. [electronic resource]
Producer: 20170926Description: 4628-4636 p. digitalISSN:- 1464-3391
- Antimalarials -- chemical synthesis
- Binding Sites
- CD13 Antigens -- antagonists & inhibitors
- Catalytic Domain
- Cell Survival -- drug effects
- Dipeptides -- chemical synthesis
- Erythrocytes -- cytology
- Human Umbilical Vein Endothelial Cells
- Humans
- Leucine -- analogs & derivatives
- Molecular Docking Simulation
- Peptidomimetics
- Plasmodium falciparum -- drug effects
- Protozoan Proteins -- antagonists & inhibitors
- Recombinant Proteins -- biosynthesis
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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