KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library.
González-Bacerio, Jorge
KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library. [electronic resource] - Bioorganic & medicinal chemistry 09 2017 - 4628-4636 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3391
10.1016/j.bmc.2017.06.047 doi
Antimalarials--chemical synthesis
Binding Sites
CD13 Antigens--antagonists & inhibitors
Catalytic Domain
Cell Survival--drug effects
Dipeptides--chemical synthesis
Erythrocytes--cytology
Human Umbilical Vein Endothelial Cells
Humans
Leucine--analogs & derivatives
Molecular Docking Simulation
Peptidomimetics
Plasmodium falciparum--drug effects
Protozoan Proteins--antagonists & inhibitors
Recombinant Proteins--biosynthesis
Structure-Activity Relationship
KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library. [electronic resource] - Bioorganic & medicinal chemistry 09 2017 - 4628-4636 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3391
10.1016/j.bmc.2017.06.047 doi
Antimalarials--chemical synthesis
Binding Sites
CD13 Antigens--antagonists & inhibitors
Catalytic Domain
Cell Survival--drug effects
Dipeptides--chemical synthesis
Erythrocytes--cytology
Human Umbilical Vein Endothelial Cells
Humans
Leucine--analogs & derivatives
Molecular Docking Simulation
Peptidomimetics
Plasmodium falciparum--drug effects
Protozoan Proteins--antagonists & inhibitors
Recombinant Proteins--biosynthesis
Structure-Activity Relationship