Hsp90 inhibitor geldanamycin attenuates the cytotoxicity of sunitinib in cardiomyocytes via inhibition of the autophagy pathway. [electronic resource]
Producer: 20170731Description: 282-292 p. digitalISSN:- 1096-0333
- Animals
- Antineoplastic Agents -- toxicity
- Autophagy -- drug effects
- Autophagy-Related Protein 7 -- genetics
- Autophagy-Related Protein-1 Homolog -- genetics
- Beclin-1 -- genetics
- Benzoquinones -- pharmacology
- Cardiotoxicity
- Cell Differentiation
- Cell Line
- Cell Lineage
- Cytoprotection
- Dose-Response Relationship, Drug
- HSP70 Heat-Shock Proteins -- genetics
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Humans
- Indoles -- toxicity
- Induced Pluripotent Stem Cells -- drug effects
- Lactams, Macrocyclic -- pharmacology
- Myocytes, Cardiac -- drug effects
- Protein Kinase Inhibitors -- toxicity
- Pyrroles -- toxicity
- RNA Interference
- Rats
- Signal Transduction -- drug effects
- Sunitinib
- Transfection
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Publication Type: Journal Article
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