MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation. [electronic resource]
Producer: 20170818Description: 139-149 p. digitalISSN:- 1873-2968
- Cell Line
- Computational Biology
- Cytochrome P-450 CYP2D6 -- chemistry
- Cytochrome P-450 CYP2D6 Inducers -- pharmacology
- Databases, Protein
- Dexamethasone -- pharmacology
- Electrophoretic Mobility Shift Assay
- Enzyme Induction -- drug effects
- Enzyme Repression
- Epigenesis, Genetic
- Expert Systems
- Glucocorticoids -- pharmacology
- Hepatocytes -- drug effects
- Humans
- Hydrolysis
- MicroRNAs -- metabolism
- Proteomics -- methods
- RNA Stability
- RNA, Messenger -- chemistry
- Recombinant Proteins -- chemistry
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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