MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation.
Zeng, Linjuan
MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation. [electronic resource] - Biochemical pharmacology 09 2017 - 139-149 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
1873-2968
10.1016/j.bcp.2017.05.018 doi
Cell Line
Computational Biology
Cytochrome P-450 CYP2D6--chemistry
Cytochrome P-450 CYP2D6 Inducers--pharmacology
Databases, Protein
Dexamethasone--pharmacology
Electrophoretic Mobility Shift Assay
Enzyme Induction--drug effects
Enzyme Repression
Epigenesis, Genetic
Expert Systems
Glucocorticoids--pharmacology
Hepatocytes--drug effects
Humans
Hydrolysis
MicroRNAs--metabolism
Proteomics--methods
RNA Stability
RNA, Messenger--chemistry
Recombinant Proteins--chemistry
MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation. [electronic resource] - Biochemical pharmacology 09 2017 - 139-149 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
1873-2968
10.1016/j.bcp.2017.05.018 doi
Cell Line
Computational Biology
Cytochrome P-450 CYP2D6--chemistry
Cytochrome P-450 CYP2D6 Inducers--pharmacology
Databases, Protein
Dexamethasone--pharmacology
Electrophoretic Mobility Shift Assay
Enzyme Induction--drug effects
Enzyme Repression
Epigenesis, Genetic
Expert Systems
Glucocorticoids--pharmacology
Hepatocytes--drug effects
Humans
Hydrolysis
MicroRNAs--metabolism
Proteomics--methods
RNA Stability
RNA, Messenger--chemistry
Recombinant Proteins--chemistry