Oxidized 5-aminosalicylic acid activates Nrf2-HO-1 pathway by covalently binding to Keap1: Implication in anti-inflammatory actions of 5-aminosalicylic acid. [electronic resource]
Producer: 20180426Description: 715-724 p. digitalISSN:- 1873-4596
- Animals
- Anti-Inflammatory Agents -- therapeutic use
- Colonic Neoplasms -- drug therapy
- HCT116 Cells
- Heme Oxygenase-1 -- metabolism
- Humans
- Hypochlorous Acid -- metabolism
- Inflammation -- drug therapy
- Inflammatory Bowel Diseases -- drug therapy
- Kelch-Like ECH-Associated Protein 1 -- metabolism
- Male
- Mesalamine -- therapeutic use
- NF-E2-Related Factor 2 -- metabolism
- Oxidation-Reduction
- Protein Binding
- Rats
- Rats, Sprague-Dawley
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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