Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice. [electronic resource]
Producer: 20170926Description: 2235-2248 p. digitalISSN:- 1558-8238
- Animals
- Cell Hypoxia
- Cell Proliferation
- Embryo, Mammalian -- pathology
- Female
- Gene Expression
- Gene Expression Regulation, Developmental
- Gene Silencing
- HEK293 Cells
- Heart Defects, Congenital -- etiology
- Histone Deacetylases -- metabolism
- Homeobox Protein Nkx-2.5 -- genetics
- Humans
- LIM-Homeodomain Proteins -- genetics
- Mice, Inbred C57BL
- Mice, Transgenic
- Myocardium -- metabolism
- Pregnancy
- Signal Transduction
- Sirtuin 1 -- genetics
- Spatio-Temporal Analysis
- Transcription Factors -- genetics
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Publication Type: Journal Article
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