Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice.

Yuan, Xuejun

Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice. [electronic resource] - The Journal of clinical investigation Jun 2017 - 2235-2248 p. digital

Publication Type: Journal Article

1558-8238

10.1172/JCI88725 doi


Animals
Cell Hypoxia
Cell Proliferation
Embryo, Mammalian--pathology
Female
Gene Expression
Gene Expression Regulation, Developmental
Gene Silencing
HEK293 Cells
Heart Defects, Congenital--etiology
Histone Deacetylases--metabolism
Homeobox Protein Nkx-2.5--genetics
Humans
LIM-Homeodomain Proteins--genetics
Mice, Inbred C57BL
Mice, Transgenic
Myocardium--metabolism
Pregnancy
Signal Transduction
Sirtuin 1--genetics
Spatio-Temporal Analysis
Transcription Factors--genetics