A chemical genomics approach to drug reprofiling in oncology: Antipsychotic drug risperidone as a potential adenocarcinoma treatment. [electronic resource]
Producer: 20170814Description: 16-21 p. digitalISSN:- 1872-7980
- 17-Hydroxysteroid Dehydrogenases -- antagonists & inhibitors
- 3-Hydroxyacyl CoA Dehydrogenases -- antagonists & inhibitors
- Adenocarcinoma -- drug therapy
- Animals
- Antineoplastic Agents -- chemistry
- Antipsychotic Agents -- chemistry
- Bacteriophage T7 -- genetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drosophila melanogaster -- drug effects
- Drug Compounding
- Drug Repositioning -- methods
- Enzyme Inhibitors -- chemistry
- Gene Library
- Genomics -- methods
- Humans
- Linoleic Acids, Conjugated -- chemistry
- Male
- Mice, Nude
- Molecular Docking Simulation
- Molecular Targeted Therapy
- Prostatic Neoplasms -- drug therapy
- Protein Conformation
- Risperidone -- chemistry
- Structure-Activity Relationship
- Time Factors
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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