A chemical genomics approach to drug reprofiling in oncology: Antipsychotic drug risperidone as a potential adenocarcinoma treatment.
Dilly, Suzanne J
A chemical genomics approach to drug reprofiling in oncology: Antipsychotic drug risperidone as a potential adenocarcinoma treatment. [electronic resource] - Cancer letters 05 2017 - 16-21 p. digital
Publication Type: Journal Article
1872-7980
10.1016/j.canlet.2017.01.042 doi
17-Hydroxysteroid Dehydrogenases--antagonists & inhibitors
3-Hydroxyacyl CoA Dehydrogenases--antagonists & inhibitors
Adenocarcinoma--drug therapy
Animals
Antineoplastic Agents--chemistry
Antipsychotic Agents--chemistry
Bacteriophage T7--genetics
Cell Line, Tumor
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drosophila melanogaster--drug effects
Drug Compounding
Drug Repositioning--methods
Enzyme Inhibitors--chemistry
Gene Library
Genomics--methods
Humans
Linoleic Acids, Conjugated--chemistry
Male
Mice, Nude
Molecular Docking Simulation
Molecular Targeted Therapy
Prostatic Neoplasms--drug therapy
Protein Conformation
Risperidone--chemistry
Structure-Activity Relationship
Time Factors
Tumor Burden--drug effects
Xenograft Model Antitumor Assays
A chemical genomics approach to drug reprofiling in oncology: Antipsychotic drug risperidone as a potential adenocarcinoma treatment. [electronic resource] - Cancer letters 05 2017 - 16-21 p. digital
Publication Type: Journal Article
1872-7980
10.1016/j.canlet.2017.01.042 doi
17-Hydroxysteroid Dehydrogenases--antagonists & inhibitors
3-Hydroxyacyl CoA Dehydrogenases--antagonists & inhibitors
Adenocarcinoma--drug therapy
Animals
Antineoplastic Agents--chemistry
Antipsychotic Agents--chemistry
Bacteriophage T7--genetics
Cell Line, Tumor
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drosophila melanogaster--drug effects
Drug Compounding
Drug Repositioning--methods
Enzyme Inhibitors--chemistry
Gene Library
Genomics--methods
Humans
Linoleic Acids, Conjugated--chemistry
Male
Mice, Nude
Molecular Docking Simulation
Molecular Targeted Therapy
Prostatic Neoplasms--drug therapy
Protein Conformation
Risperidone--chemistry
Structure-Activity Relationship
Time Factors
Tumor Burden--drug effects
Xenograft Model Antitumor Assays