Balanced secretion of anti-CEA × anti-CD3 diabody chains using the 2A self-cleaving peptide maximizes diabody assembly and tumor-specific cytotoxicity. [electronic resource]
Producer: 20170508Description: 208-214 p. digitalISSN:- 1476-5462
- Antibodies, Bispecific -- genetics
- CD3 Complex -- genetics
- Carcinoembryonic Antigen -- immunology
- Cytotoxicity, Immunologic
- Foot-and-Mouth Disease Virus -- genetics
- Humans
- Immunotherapy -- methods
- Jurkat Cells
- Lymphocyte Activation -- immunology
- Neoplasms -- immunology
- Peptides -- genetics
- Single-Chain Antibodies -- genetics
- T-Lymphocytes -- immunology
- Tumor Necrosis Factor Receptor Superfamily, Member 7 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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