CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis. [electronic resource]
Producer: 20170613Description: 914-922 p. digitalISSN:- 1468-2060
- Animals
- Cartilage, Articular -- pathology
- Chemokine CCL2 -- genetics
- Chemokine CCL5 -- genetics
- Chemokines -- genetics
- Chemotaxis
- Fibroblasts -- metabolism
- Gene Expression
- Humans
- Indazoles -- pharmacology
- Leukocyte Count
- Macrophages
- Male
- Mice, Inbred C57BL
- Mice, Knockout
- Monocytes -- physiology
- Osteoarthritis -- metabolism
- Propionates -- pharmacology
- RNA, Messenger -- metabolism
- Receptors, CCR2 -- antagonists & inhibitors
- Receptors, CCR5 -- genetics
- Signal Transduction -- drug effects
- Synovial Fluid -- metabolism
No physical items for this record
Publication Type: Journal Article
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