Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease. [electronic resource]
Producer: 20170214Description: 212-224 p. digitalISSN:- 2352-3964
- Animals
- Cell Line
- Disease Models, Animal
- Fibroblasts -- drug effects
- Gaucher Disease -- drug therapy
- Glucosylceramidase -- metabolism
- HSP70 Heat-Shock Proteins -- genetics
- Humans
- Intercellular Signaling Peptides and Proteins -- genetics
- Lysosomal Membrane Proteins -- metabolism
- Lysosomes -- metabolism
- Mice
- Mice, Knockout
- Phenotype
- Progranulins
- Protein Aggregates
- Protein Binding
- Recombinant Proteins -- pharmacology
- Stress, Physiological
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Publication Type: Journal Article
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