Phosphorylation of MITF by AKT affects its downstream targets and causes TP53-dependent cell senescence. [electronic resource]
Producer: 20171107Description: 132-142 p. digitalISSN:- 1878-5875
- Cell Line, Tumor
- Cell Proliferation
- Cellular Senescence
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Gene Expression Regulation, Neoplastic
- Humans
- Inhibitor of Differentiation Proteins -- metabolism
- Melanoma -- metabolism
- Microphthalmia-Associated Transcription Factor -- metabolism
- Phosphorylation
- Proteolysis
- Proto-Oncogene Proteins c-akt -- metabolism
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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