Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury. [electronic resource]
Producer: 20171121Description: 649-663 p. digitalISSN:- 2213-6711
- Amyloid Precursor Protein Secretases -- antagonists & inhibitors
- Animals
- Biomarkers
- Cell Proliferation
- Cell Transformation, Neoplastic
- Disease Models, Animal
- Epithelial-Mesenchymal Transition
- Gene Expression Profiling
- Humans
- Induced Pluripotent Stem Cells -- cytology
- Locomotion
- Mice
- Neoplasms -- etiology
- Neural Stem Cells -- cytology
- Neurons -- metabolism
- Protease Inhibitors -- pharmacology
- Spinal Cord Injuries -- pathology
- Stem Cell Transplantation -- adverse effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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