Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury.
Okubo, Toshiki
Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury. [electronic resource] - Stem cell reports 10 2016 - 649-663 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2213-6711
10.1016/j.stemcr.2016.08.015 doi
Amyloid Precursor Protein Secretases--antagonists & inhibitors
Animals
Biomarkers
Cell Proliferation
Cell Transformation, Neoplastic
Disease Models, Animal
Epithelial-Mesenchymal Transition
Gene Expression Profiling
Humans
Induced Pluripotent Stem Cells--cytology
Locomotion
Mice
Neoplasms--etiology
Neural Stem Cells--cytology
Neurons--metabolism
Protease Inhibitors--pharmacology
Spinal Cord Injuries--pathology
Stem Cell Transplantation--adverse effects
Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury. [electronic resource] - Stem cell reports 10 2016 - 649-663 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2213-6711
10.1016/j.stemcr.2016.08.015 doi
Amyloid Precursor Protein Secretases--antagonists & inhibitors
Animals
Biomarkers
Cell Proliferation
Cell Transformation, Neoplastic
Disease Models, Animal
Epithelial-Mesenchymal Transition
Gene Expression Profiling
Humans
Induced Pluripotent Stem Cells--cytology
Locomotion
Mice
Neoplasms--etiology
Neural Stem Cells--cytology
Neurons--metabolism
Protease Inhibitors--pharmacology
Spinal Cord Injuries--pathology
Stem Cell Transplantation--adverse effects