Targeting of NADPH oxidase in vitro and in vivo suppresses fibroblast activation and experimental skin fibrosis. [electronic resource]
Producer: 20180226Description: 73-81 p. digitalISSN:- 1600-0625
- Actins -- genetics
- Adult
- Animals
- Cells, Cultured
- Collagen Type I -- genetics
- Collagen Type I, alpha 1 Chain
- Computer Simulation
- Cytokines -- genetics
- Disease Models, Animal
- Enzyme Inhibitors -- pharmacology
- Female
- Fibroblasts -- enzymology
- Fibronectins
- Fibrosis
- Gene Expression -- drug effects
- Gene Expression Profiling
- Gene Silencing
- Humans
- Infant, Newborn
- Isoenzymes -- genetics
- Male
- Mice
- Middle Aged
- Multienzyme Complexes -- metabolism
- Myofibroblasts
- NADH, NADPH Oxidoreductases -- metabolism
- NADPH Oxidase 1 -- genetics
- NADPH Oxidase 2 -- genetics
- NADPH Oxidase 4 -- genetics
- Onium Compounds -- pharmacology
- Primary Cell Culture
- RNA, Messenger -- metabolism
- Scleroderma, Systemic -- chemically induced
- Skin -- enzymology
- Transforming Growth Factor beta -- pharmacology
- Young Adult
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Publication Type: Journal Article
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