SIRT1-mediated deacetylation of PGC1α attributes to the protection of curcumin against glutamate excitotoxicity in cortical neurons. [electronic resource]
Producer: 20170529Description: 1376-81 p. digitalISSN:- 1090-2104
- Acetylation -- drug effects
- Adenosine Triphosphate -- metabolism
- Animals
- Benzamides -- pharmacology
- Calcium -- metabolism
- Cell Death -- drug effects
- Cells, Cultured
- Cerebral Cortex -- pathology
- Curcumin -- pharmacology
- Electron Transport Complex IV -- metabolism
- Glutamic Acid -- toxicity
- Intracellular Space -- metabolism
- Membrane Potential, Mitochondrial -- drug effects
- Mitochondria -- drug effects
- Naphthols -- pharmacology
- Neurons -- drug effects
- Neuroprotection -- drug effects
- Neuroprotective Agents -- pharmacology
- Neurotoxins -- toxicity
- Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha -- metabolism
- Rats, Sprague-Dawley
- Reactive Oxygen Species -- metabolism
- Sirtuin 1 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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