The histone demethylase inhibitor GSK-J4 limits inflammation through the induction of a tolerogenic phenotype on DCs. [electronic resource]
Producer: 20170601Description: 105-117 p. digitalISSN:- 1095-9157
- Adoptive Transfer
- Animals
- Antigens, CD -- immunology
- B7-1 Antigen -- immunology
- B7-2 Antigen -- immunology
- Benzazepines -- pharmacology
- Blotting, Western
- CD4-Positive T-Lymphocytes -- immunology
- Cytokines -- genetics
- Dendritic Cells -- drug effects
- Encephalomyelitis, Autoimmune, Experimental -- genetics
- Gene Expression -- drug effects
- Immune Tolerance -- genetics
- Inflammation Mediators -- immunology
- Integrin alpha Chains -- immunology
- Jumonji Domain-Containing Histone Demethylases -- antagonists & inhibitors
- Mice, Inbred C57BL
- Mice, Transgenic
- Phenotype
- Pyrimidines -- pharmacology
- Reverse Transcriptase Polymerase Chain Reaction
- Transforming Growth Factor beta1 -- immunology
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Publication Type: Journal Article
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