Insulin-like growth factor 1 rescues R28 retinal neurons from apoptotic death through ERK-mediated BimEL phosphorylation independent of Akt. [electronic resource]
Producer: 20170601Description: 82-95 p. digitalISSN:- 1096-0007
- Animals
- Apoptosis -- drug effects
- Blotting, Western
- Cell Line
- Cell Survival
- Disease Models, Animal
- Gene Expression Regulation
- Insulin-Like Growth Factor I -- pharmacology
- Microscopy, Confocal
- Mitogen-Activated Protein Kinase 3 -- biosynthesis
- Phosphorylation
- Proto-Oncogene Proteins c-akt -- biosynthesis
- RNA -- genetics
- Rats
- Rats, Sprague-Dawley
- Real-Time Polymerase Chain Reaction
- Retinal Ganglion Cells -- metabolism
- Signal Transduction
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
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