Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency. [electronic resource]
Producer: 20170217Description: 14-20 p. digitalISSN:- 1768-3254
- Cell Line, Tumor
- Enzyme Inhibitors -- chemistry
- Enzyme Replacement Therapy -- methods
- Enzyme Stability -- drug effects
- Fabry Disease -- drug therapy
- Humans
- Imino Pyranoses -- chemistry
- Imino Sugars -- chemical synthesis
- Mannitol -- analogs & derivatives
- Pyrrolidines -- chemical synthesis
- Small Molecule Libraries -- chemistry
- Stereoisomerism
- alpha-Galactosidase -- drug effects
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Publication Type: Journal Article
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