Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency.
Cheng, Wei-Chieh
Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency. [electronic resource] - European journal of medicinal chemistry Nov 2016 - 14-20 p. digital
Publication Type: Journal Article
1768-3254
10.1016/j.ejmech.2016.07.025 doi
Cell Line, Tumor
Enzyme Inhibitors--chemistry
Enzyme Replacement Therapy--methods
Enzyme Stability--drug effects
Fabry Disease--drug therapy
Humans
Imino Pyranoses--chemistry
Imino Sugars--chemical synthesis
Mannitol--analogs & derivatives
Pyrrolidines--chemical synthesis
Small Molecule Libraries--chemistry
Stereoisomerism
alpha-Galactosidase--drug effects
Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency. [electronic resource] - European journal of medicinal chemistry Nov 2016 - 14-20 p. digital
Publication Type: Journal Article
1768-3254
10.1016/j.ejmech.2016.07.025 doi
Cell Line, Tumor
Enzyme Inhibitors--chemistry
Enzyme Replacement Therapy--methods
Enzyme Stability--drug effects
Fabry Disease--drug therapy
Humans
Imino Pyranoses--chemistry
Imino Sugars--chemical synthesis
Mannitol--analogs & derivatives
Pyrrolidines--chemical synthesis
Small Molecule Libraries--chemistry
Stereoisomerism
alpha-Galactosidase--drug effects