Targeting Homologous Recombination by Pharmacological Inhibitors Enhances the Killing Response of Glioblastoma Cells Treated with Alkylating Drugs. [electronic resource]
Producer: 20170615Description: 2665-2678 p. digitalISSN:- 1538-8514
- Animals
- Antineoplastic Agents, Alkylating -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Survival -- drug effects
- Chromosome Aberrations -- drug effects
- DNA Damage
- DNA Modification Methylases -- metabolism
- DNA Repair
- DNA Repair Enzymes -- metabolism
- DNA Replication -- drug effects
- DNA-Binding Proteins -- metabolism
- Disease Models, Animal
- Glioblastoma -- drug therapy
- Homologous Recombination -- drug effects
- Humans
- Lomustine -- pharmacology
- MRE11 Homologue Protein
- Mice
- Rad51 Recombinase -- metabolism
- Tumor Suppressor Proteins -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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