Leukaemia-associated Rho guanine nucleotide exchange factor (LARG) plays an agonist specific role in platelet function through RhoA activation. [electronic resource]
Producer: 20180129Description: 506-16 p. digitalISSN:- 2567-689X
- Animals
- Bleeding Time
- Blood Platelets -- drug effects
- Gene Knockdown Techniques
- Humans
- Megakaryocytes -- cytology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Myosin Light Chains -- blood
- Platelet Function Tests
- Rho Guanine Nucleotide Exchange Factors -- antagonists & inhibitors
- Thrombin -- metabolism
- Thrombopoiesis -- genetics
- Thromboxanes -- blood
- rho GTP-Binding Proteins -- agonists
- rhoA GTP-Binding Protein -- agonists
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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