Leukaemia-associated Rho guanine nucleotide exchange factor (LARG) plays an agonist specific role in platelet function through RhoA activation.
Zou, Siying
Leukaemia-associated Rho guanine nucleotide exchange factor (LARG) plays an agonist specific role in platelet function through RhoA activation. [electronic resource] - Thrombosis and haemostasis 08 2016 - 506-16 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
2567-689X
10.1160/TH15-11-0848 doi
Animals
Bleeding Time
Blood Platelets--drug effects
Gene Knockdown Techniques
Humans
Megakaryocytes--cytology
Mice
Mice, Inbred C57BL
Mice, Knockout
Myosin Light Chains--blood
Platelet Function Tests
Rho Guanine Nucleotide Exchange Factors--antagonists & inhibitors
Thrombin--metabolism
Thrombopoiesis--genetics
Thromboxanes--blood
rho GTP-Binding Proteins--agonists
rhoA GTP-Binding Protein--agonists
Leukaemia-associated Rho guanine nucleotide exchange factor (LARG) plays an agonist specific role in platelet function through RhoA activation. [electronic resource] - Thrombosis and haemostasis 08 2016 - 506-16 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
2567-689X
10.1160/TH15-11-0848 doi
Animals
Bleeding Time
Blood Platelets--drug effects
Gene Knockdown Techniques
Humans
Megakaryocytes--cytology
Mice
Mice, Inbred C57BL
Mice, Knockout
Myosin Light Chains--blood
Platelet Function Tests
Rho Guanine Nucleotide Exchange Factors--antagonists & inhibitors
Thrombin--metabolism
Thrombopoiesis--genetics
Thromboxanes--blood
rho GTP-Binding Proteins--agonists
rhoA GTP-Binding Protein--agonists