A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer. [electronic resource]
Producer: 20170807Description: 744-53 p. digitalISSN:- 1546-170X
- Animals
- Aurora Kinase A -- antagonists & inhibitors
- Azepines -- pharmacology
- Carcinoma, Hepatocellular -- drug therapy
- Cell Cycle Checkpoints
- Cyclin-Dependent Kinase Inhibitor p16 -- genetics
- Gene Deletion
- Hepatocytes -- metabolism
- Humans
- Liver Neoplasms -- drug therapy
- Liver Neoplasms, Experimental -- drug therapy
- Mice
- Mice, Knockout
- Molecular Targeted Therapy
- Monomeric GTP-Binding Proteins -- genetics
- Mutation
- Oncogene Protein p21(ras) -- metabolism
- Phenylurea Compounds -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-myc -- metabolism
- Pyrimidines -- pharmacology
- RNA, Small Interfering
- Tumor Suppressor Protein p53 -- genetics
- Xenograft Model Antitumor Assays
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.