A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer. (Record no. 26049295)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02342 a2200697 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517095404.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201708s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1546-170X |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/nm.4107 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Dauch, Daniel |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20170807 |
| 245 00 - TITLE STATEMENT | |
| Title | A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Nature medicine |
| Date of publication, distribution, etc. | 07 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 744-53 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Aurora Kinase A |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Azepines |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Carcinoma, Hepatocellular |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Cycle Checkpoints |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cyclin-Dependent Kinase Inhibitor p16 |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Gene Deletion |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hepatocytes |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Liver Neoplasms |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Liver Neoplasms, Experimental |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Knockout |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Targeted Therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Monomeric GTP-Binding Proteins |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Oncogene Protein p21(ras) |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phenylurea Compounds |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Kinase Inhibitors |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proto-Oncogene Proteins c-myc |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrimidines |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | RNA, Small Interfering |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Tumor Suppressor Protein p53 |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Xenograft Model Antitumor Assays |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rudalska, Ramona |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cossa, Giacomo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nault, Jean-Charles |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kang, Tae-Won |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wuestefeld, Torsten |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hohmeyer, Anja |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Imbeaud, Sandrine |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yevsa, Tetyana |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hoenicke, Lisa |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pantsar, Tatu |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bozko, Przemyslaw |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Malek, Nisar P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Longerich, Thomas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Laufer, Stefan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Poso, Antti |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zucman-Rossi, Jessica |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eilers, Martin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zender, Lars |
| 773 0# - HOST ITEM ENTRY | |
| Title | Nature medicine |
| Related parts | vol. 22 |
| -- | no. 7 |
| -- | p. 744-53 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/nm.4107">https://doi.org/10.1038/nm.4107</a> |
| Public note | Available from publisher's website |
No items available.