The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells. [electronic resource]
Producer: 20170330Description: 74-88 p. digitalISSN:- 1791-2423
- Apoptosis -- drug effects
- CASP8 and FADD-Like Apoptosis Regulating Protein -- biosynthesis
- Caspase 8 -- biosynthesis
- Cell Line, Tumor
- Drug Resistance, Neoplasm -- genetics
- Drug Synergism
- Gene Expression Regulation, Leukemic -- drug effects
- Humans
- Myeloid Cell Leukemia Sequence 1 Protein -- biosynthesis
- Oxazepines -- administration & dosage
- Phosphatidylinositol 3-Kinases -- genetics
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- drug therapy
- Pyrroles -- administration & dosage
- Receptors, TNF-Related Apoptosis-Inducing Ligand -- biosynthesis
- Signal Transduction -- drug effects
- TNF-Related Apoptosis-Inducing Ligand -- administration & dosage
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.