Neoadjuvant tamoxifen synchronizes ERα binding and gene expression profiles related to outcome and proliferation. [electronic resource]
Producer: 20171221Description: 33901-18 p. digitalISSN:- 1949-2553
- Adult
- Aged
- Biomarkers, Tumor -- genetics
- Breast Neoplasms -- drug therapy
- Cell Proliferation -- drug effects
- Chemotherapy, Adjuvant
- Chromatin -- genetics
- DNA Copy Number Variations
- Estrogen Receptor alpha -- drug effects
- Female
- Gene Dosage
- Gene Expression Profiling -- methods
- Gene Expression Regulation, Neoplastic -- drug effects
- Hepatocyte Nuclear Factor 3-alpha -- genetics
- Humans
- MCF-7 Cells
- Middle Aged
- Neoadjuvant Therapy
- Netherlands
- Patient Selection
- Precision Medicine
- Predictive Value of Tests
- Protein Binding
- Selective Estrogen Receptor Modulators -- administration & dosage
- Tamoxifen -- administration & dosage
- Time Factors
- Transcription, Genetic
- Transcriptome -- drug effects
- Treatment Outcome
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Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial
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