Calcium influx-mediated translocation of m-calpain induces Ku80 cleavage and enhances the Ku80-related DNA repair pathway. [electronic resource]
Producer: 20171229Description: 30831-44 p. digitalISSN:- 1949-2553
- Antineoplastic Agents -- pharmacology
- Calcium -- metabolism
- Calcium Ionophores -- pharmacology
- Calpain -- genetics
- Cell Line
- Cell-Free System -- metabolism
- DNA Breaks, Double-Stranded
- DNA End-Joining Repair -- physiology
- Drug Resistance, Neoplasm
- Epithelial Cells -- drug effects
- Gene Knockdown Techniques
- Humans
- Ionomycin -- pharmacology
- Ku Autoantigen -- metabolism
- Molecular Targeted Therapy -- methods
- Neoplasms -- drug therapy
- Protein Binding
- Protein Domains -- physiology
- Protein Multimerization -- physiology
- Protein Transport -- physiology
- Proteolysis
- Proteomics
- RNA Interference
- RNA, Small Interfering
- Recombinant Proteins -- genetics
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Publication Type: Journal Article
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