Calcium influx-mediated translocation of m-calpain induces Ku80 cleavage and enhances the Ku80-related DNA repair pathway.

Baek, Kyung Hye

Calcium influx-mediated translocation of m-calpain induces Ku80 cleavage and enhances the Ku80-related DNA repair pathway. [electronic resource] - Oncotarget May 2016 - 30831-44 p. digital

Publication Type: Journal Article

1949-2553

10.18632/oncotarget.8791 doi


Antineoplastic Agents--pharmacology
Calcium--metabolism
Calcium Ionophores--pharmacology
Calpain--genetics
Cell Line
Cell-Free System--metabolism
DNA Breaks, Double-Stranded
DNA End-Joining Repair--physiology
Drug Resistance, Neoplasm
Epithelial Cells--drug effects
Gene Knockdown Techniques
Humans
Ionomycin--pharmacology
Ku Autoantigen--metabolism
Molecular Targeted Therapy--methods
Neoplasms--drug therapy
Protein Binding
Protein Domains--physiology
Protein Multimerization--physiology
Protein Transport--physiology
Proteolysis
Proteomics
RNA Interference
RNA, Small Interfering
Recombinant Proteins--genetics