Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells. [electronic resource]
Producer: 20180112Description: 4440-51 p. digitalISSN:- 1557-3265
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Bcl-2-Like Protein 11 -- metabolism
- Bridged Bicyclo Compounds, Heterocyclic -- pharmacology
- Cell Line, Tumor
- Cytarabine -- pharmacology
- Daunorubicin -- pharmacology
- Drug Resistance, Neoplasm
- Drug Synergism
- Humans
- Leukemia, Myeloid, Acute -- drug therapy
- Myeloid Cell Leukemia Sequence 1 Protein -- metabolism
- Protein Stability -- drug effects
- Sulfonamides -- pharmacology
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Publication Type: Journal Article
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