Sevoflurane inhibits embryonic stem cell self-renewal and subsequent neural differentiation by modulating the let-7a-Lin28 signaling pathway. [electronic resource]
Producer: 20170515Description: 319-30 p. digitalISSN:- 1432-0878
- Anesthesia
- Animals
- Apoptosis -- drug effects
- Biomarkers -- metabolism
- Brain -- drug effects
- Cell Differentiation -- drug effects
- Cell Self Renewal -- drug effects
- Cell Survival -- drug effects
- Down-Regulation -- drug effects
- Embryonic Development -- drug effects
- Female
- Gene Expression Regulation, Developmental -- drug effects
- Male
- Methyl Ethers -- pharmacology
- Mice
- Mice, Inbred C57BL
- MicroRNAs -- metabolism
- Mouse Embryonic Stem Cells -- cytology
- Neurons -- cytology
- RNA-Binding Proteins -- metabolism
- Sevoflurane
- Signal Transduction -- drug effects
- Up-Regulation -- drug effects
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Publication Type: Journal Article
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